Gentle Microbiome Support for Sensitive Stomachs, Including GLP-1 Users
A Probiotic That Actually Works With Your Sensitive Gut
Whether you're managing GLP-1 side effects or living with a sensitive stomach, you've probably learned the hard way that most probiotics make things worse. Many formulas rely on prebiotic fibers and fillers that can trigger gas and bloating. When digestion is slowed or reactive, "more" isn't better. It has to be the right strains, in a formula your gut can actually tolerate.
Casa de Sante Advanced Probiotics GI Support is formulated for digestion that doesn't work the way it should, whether that's medication-induced or just how your gut is wired. Each capsule provides 5.75 billion CFU of a targeted multi-strain blend, including Lactobacillus and Bifidobacterium strains to support a balanced gut microbiome, plus DE111® (Bacillus subtilis), a spore-forming strain selected for stability through heat and stomach acid.
It's also designed without common high-FODMAP fillers like inulin, chicory root fiber, fructooligosaccharides, and lactose-based carriers, so sensitive stomachs are less likely to react.
This is daily GI support you can stick with, even when your gut is picky.
Who It's For
People taking GLP-1 medications (Ozempic, Wegovy, Mounjaro, Zepbound) who want gentle gut support, and anyone managing IBS, SIBO, food sensitivities, or a low-FODMAP lifestyle, including those in perimenopause or menopause.
5.75 Billion CFU
Supports Digestive Comfort & Balanced Microbiome
A clinically relevant mix of strains supports a healthy gut microbial community, which supports normal digestive function and comfort.
Designed for Sensitive Digestion
By excluding common trigger fibers and using a shelf-stable, spore-supported blend, this formula is built for people who don't tolerate "standard" probiotics.
Supports Gut Barrier Integrity
A healthy microbiome supports the gut barrier and the body's normal inflammatory response, which can influence how you feel day to day.
Supports Gut-Hormone Axis Wellness
The microbiome plays a role in normal estrogen metabolite processing and overall gut-hormone communication, supporting mood, sleep quality, and whole-body comfort during perimenopause and menopause.
Physician-Formulated Excellence
Created by Dr. Onyx Adegbola, MD PhD (Columbia MD, Johns Hopkins PhD), board certified in obesity medicine and menopause management. This formula represents expert-backed, science-driven microbiome support.
Low-FODMAP Gut Friendly Shelf-Stable No Refrigeration Required 7 Targeted Strains Spore-Forming Technology No Common Triggers
Premium Probiotic Strains
Probiotic Bacteria (5.75 Billion CFU) - 9mg
DE111® (Bacillus subtilis)
Lactobacillus rhamnosus
Lactobacillus casei
Bifidobacterium longum
Lactobacillus acidophilus
Lactobacillus plantarum
Bifidobacterium breve
Other Ingredients: Vegetable cellulose, maltodextrin, and medium chain triglycerides
How to Use
Take 1 capsule daily, with or without food
Give it 4–8 weeks of consistent use, and choose the probiotic made for the people who react to everything else.
Important Disclaimer: These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Ready to Support Your Sensitive Gut?
Experience the difference of a probiotic formula designed specifically for reactive, sensitive digestion. No common triggers. Just targeted support.
Shop GI Support
Evidence and quality: what backs this product
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Third-party tested — independent lab verified, made in a cGMP facility.
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FODMAP-conscious formulation — no high-FODMAP fillers such as inulin or chicory root.
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Formulated by Onikepe Adegbola, MD, PhD, a physician-scientist and the founder of Casa de Sante.
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Price: $22.99 (direct from Casa de Sante).
What this product cannot do
Advanced Probiotics GI Support is a dietary supplement, not a medicine. It does not treat, cure or prevent IBS, SIBO, or any disease, it does not replace a low-FODMAP elimination diet or prescribed therapy, and it will not stop symptoms caused by an untreated medical condition. If you have new, severe, or changing GI symptoms, or you are pregnant, nursing, or on prescription medication (including GLP-1 medication), speak to your clinician first.
Frequently asked questions
Is this probiotic low FODMAP?
Yes. It is formulated without high-FODMAP prebiotic fibers such as inulin, chicory root or FOS, which are common bloating triggers for people with IBS or SIBO.
How long before I notice a difference?
Most people trial a daily probiotic for 4 weeks before judging it. Some notice changes in stool regularity within the first two weeks; response varies by individual.
Can I take it with a GLP-1 medication like semaglutide or tirzepatide?
Many customers use it while on GLP-1 therapy for regularity support. It is a food supplement, not a drug, but check with your prescriber before adding anything alongside prescription medication.
Do I need to refrigerate it?
No. Store it in a cool, dry place away from direct sunlight.
When should I take it?
One serving daily, at a consistent time. With or without food is fine — consistency matters more than timing.
Is it third-party tested?
Yes — independent lab verified and produced in a cGMP facility.
Product details and price last verified September 17, 2026.
